What is Esgic Plus?
Esgic Plus is an analgesic, barbiturate, and stimulant
combination used to relieve complex tension (muscle contraction)
headaches. Precisely how the combination works is still unknown.
What are the most common
side effects of Esgic Plus?
Serious side effects of Esgic Plus include (but are not
limited to): an allergic reaction (difficulty breathing; closing
of your throat; swelling of your lips, tongue, or face; or
hives); slow, weak breathing; liver damage (yellowing of the
skin or eyes, nausea, abdominal pain or discomfort, unusual
bleeding or bruising, severe fatigue); blood problems (easy or
unusual bleeding or bruising); low blood sugar (fatigue,
increased hunger or thirst, dizziness, or fainting.
Continue to take Esgic Plus if
you experience drowsiness; dizziness, confusion or
lightheadedness shortness of breath, dry mouth; nausea,
vomiting, abdominal pain, or decreased appetite, tiredness, leg
pain, or muscle weakness; agitation, irritability, nervousness,
anxiety or excitability rash or itching, feeling of
intoxication, headache; or constipation and contact your
physician. Other, less serious side effects may be more likely
How do I take Esgic Plus?
Esgic Plus should be taken according to your physician’s
directions. Take each dose of Esgic Plus with a full glass of
What if I miss a dose?
Do not take a double dose of Esgic Plus. Take the missed
dose of Esgic Plus as soon as you remember. If it is almost
time for your next dose, skip the missed dose and go back to
taking Esgic Plus on your regular dosing schedule.
Are there any drug
interactions with Esgic Plus?
Do not take Esgic Plus if you have taken a monoamine oxidase
inhibitor in the last 14 days. Acetaminophen and butalbital may
increase the effects of other drugs that cause drowsiness,
including antidepressants, alcohol, antihistamines, sedatives
(used to treat insomnia), other pain relievers, anxiety
medicines, and muscle relaxants. Tell your doctor about all
medicines that you are taking, and do not take any medicine
unless your doctor approves. Many other medicines contain
acetaminophen, especially over-the-counter pain, fever, cold,
and allergy medications. Too much acetaminophen can be very
dangerous. Drugs other than those listed here may also interact
with Esgic Plus. Talk to your doctor and pharmacist before
taking any prescription or over-the-counter medicine.
Is there any additional
information about Esgic Plus that I should know?
Avoid sleeping pills, antihistamines, sedatives, and
tranquilizers except under the supervision of your doctor. These
may also make you drowsy Use caution when driving, operating
machinery, or performing other hazardous activities. Butalbital
will cause drowsiness or dizziness. Avoid alcohol. Alcohol taken
during therapy with acetaminophen and butalbital can be very
damaging to your liver and can increase drowsiness and
dizziness. Never take more Esgic Plus than is prescribed for
you. If your pain is not being adequately treated, talk to your
How should I store Esgic
Store Esgic Plus at room temperature away from moisture and
heat. Keep out of reach of children.